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. 2023 Mar 7;30(10):1376–1388. doi: 10.5551/jat.64024

Table 4. Characteristics of subjects staple foods skippers or eaters by age group.

(A) Male Subjects Younger <55 y.o Older ≥ 55 y.o

SS

n=912

SE

n=3,793

P value

SS

n=906

SE

n=3,494

P value
lipids Age, year 47.0 (9.0) 46.0 (9.0) 0.004§ 61.0 (10.0) 63.0 (11.0) <0.001§
BMI, kg/m2* 23.5 (3.7) 23.4 (3.9) 0.344§ 23.4 (3.3) 23.1 (3.5) 0.001§
Waist circumference, cm 83.0 (11.0) 82.8 (10.9) 0.492§ 84.0 (9.6) 83.5 (10.3) 0.002§
Albumin, g/dL 4.4 (0.3) 4.4 (0.3) 0.154§ 4.3 (0.3) 4.2 (0.3) 0.145§
Creatinine, mg/dL 0.92 (0.16) 0.92 (0.16) 0.378§ 0.92 (0.17) 0.92 (0.18) 0.144§
ALT, IU/L 22.0 (14.0) 22.0 (15.0) 0.024§ 20.0 (10.0) 19.0 (11.0) 0.473§
Total cholesterol, mg/dl 199.0 (41.0) 197.0 (40.0) 0.006§ 204.0 (39.3) 199.0 (40.0) 0.001§
Triglycerides, mg/dL 93.0 (72.0) 94.0 (74.0) 0.829§ 96.5 (68.3) 92.0 (62.0) 0.018§
Direct LDL-C, mg/dL 121.0 (40.0) 122.0 (38.0) 0.740§ 122.0 (37.0) 121.0 (37.0) 0.962§
Calculated LDL-C, mg/dL 118.9 (38.4) 118.4 (35.8) 0.587§ 121.5 (37.3) 120.6 (35.8) 0.880§
sdLDL-C, mg/dL 33.7 (23.4) 31.6 (22.7) 0.007§ 34.4 (22.3) 31.5 (20.6) <0.001§
sdLDL-C/LDL-C ratio 0.274 (0.158) 0.253 (0.151) <0.001§ 0.283 (0.158) 0.258 (0.141) <0.001§
nonHDL-C, mg/dL 140.0 (42.3) 141.0 (42.0) 0.679§ 144.0 (37.0) 142.0 (41.0) 0.188§
HDL-C, mg/dL 56.0 (17.0) 54.0 (17.0) <0.001§ 58.0 (18.0) 56.0 (18.0) <0.001§
Diabetes treatment, n (%)** 22 (2.4%) 93 (2.5%) 0.945† 54 (6.0%) 257 (7.4%) 0.144†
Diabetes, n (%)** 50 (5.5%) 161 (4.2%) 0.105† 103 (11.4%) 415 (11.9%) 0.672†
Hypertension treatment, n (%)** 78 (8.6%) 268 (7.1%) 0.122† 269 (29.7%) 921 (26.4%) 0.044†
Hypertension, n (%)** 199 (21.8%) 661 (17.4%) 0.002† 412 (45.5%) 1455 (41.6%) 0.038†
Smoker, n (%)** 465 (51.0%) 1,761 (46.4%) 0.013† 598 (66.0%) 2,069 (59.2%) <0.001†
Drinker, n (%)** 290 (31.8%) 778 (20.5%) <0.001 402 (44.4%) 1,182 (33.8%) <0.001
Snack eater, n (%)** 140 (15.4%) 764 (20.1%) 0.001 161 (17.8%) 786 (22.5%) 0.002
(B) Female Subjects Younger <55 y.o Older ≥ 55 y.o

SS

n=1,188

SE

n=3,404

P value

SS

n=921

SE

n=2,220

P value
lipids Age, year 47.0 (9.0) 46.0 (9.0) <0.001§ 61.0 (10.0) 62.0 (10.0) <0.001§
BMI, kg/m2* 20.9 (3.6) 20.6 (3.7) 0.016§ 21.2 (3.8) 21.0 (4.0) 0.043§
Waist circumference, cm 74.5 (10.6) 74.0 (10.7) 0.159§ 77.2 (11.1) 76.8 (11.9) 0.061§
Albumin, g/dL 4.2 (0.3) 4.3 (0.3) 0.254§ 4.2 (0.3) 4.2 (0.3) 0.487§
Creatinine, mg/dL 0.68 (0.13) 0.67 (0.12) <0.001§ 0.70 (0.14) 0.70 (0.14) 0.964§
ALT, IU/L 14.0 (8.0) 14.0 (8.0) 0.275§ 16.0 (7.0) 17.0 (9.0) 0.249§
Total cholesterol, mg/dl 197.5 (45.0) 195.0 (44.0) 0.065§ 224.0 (42.0) 223.5 (40.0) 0.603§
Triglycerides, mg/dL 61.0 (34.0) 62.0 (35.0) 0.322§ 73.0 (44.0) 75.0 (41.0) 0.667§
Direct LDL-C, mg/dL 112.0 (41.0) 111.0 (39.0) 0.967§ 131.0 (39.5) 132.0 (36.0) 0.375§
Calculated LDL-C, mg/dL 113.0 (38.4) 112.0 (38.8) 0.479§ 134.2 (37.4) 135.6 (35.6) 0.486§
sdLDL-C, mg/dL 23.3 (11.7) 22.6 (11.5) 0.053§ 29.4 (15.1) 28.1 (13.0) 0.007§
sdLDL-C/LDL-C ratio 0.207 (0.066) 0.204 (0.062) 0.002§ 0.224 (0.077) 0.215 (0.064) <0.001§
nonHDL-C, mg/dL 127.0 (42.0) 126.0 (42.0) 0.647§ 151.0 (41.0) 152.0 (38.0) 0.729§
HDL-C, mg/dL 69.0 (19.0) 68.0 (18.0) 0.002§ 72.0 (21.0) 71.0 (20.0) 0.082§
Diabetes treatment, n (%)** 7 (0.6%) 11 (0.3%) 0.206 15 (1.6%) 23 (1.0%) 0.167
Diabetes, n (%)** 11 (0.9%) 13 (0.4%) 0.025 17 (1.8%) 35 (1.6%) 0.590
Hypertension treatment, n (%)** 39 (3.3%) 89 (2.6%) 0.228 140 (15.2%) 306 (13.8%) 0.300
Hypertension, n (%)** 95 (8.0%) 270 (7.9%) 0.943 258 (28.0%) 581 (26.2%) 0.288
Smoker, n (%)** 203 (17.1%) 394 (11.6%) <0.001 129 (14.0%) 175 (7.9%) <0.001
Drinker, n (%)** 201 (16.9%) 255 (7.5%) <0.001 195 (21.2%) 210 (9.5%) <0.001
Snack eater, n (%)** 614 (51.7%) 2,013 (59.1%) <0.001 394 (42.8%) 1,160 (52.3%) <0.001

Data are expressed as median (interquartile range). §Parameters were compared using T-test. P value <0.05 was considered statistically significant. Variable was log-transformed prior to formal statistical analysis. **Data are expressed as number (percentage of) in cohort. Parameters were compared using chi-square test. P value <0.05 was considered statistically significant.

“Diabetes” was defined as using anti-diabetic medication or having fasting blood glucose level >125 mg/dL. “Hypertension” was defined as using anti-hypertensive drugs or having systolic blood pressure >139 mmHg or diastolic blood pressure >89 mmHg. “Smoker” was defined as current

smokers and ex-smokers. “Drinker” was defined as consuming alcohol every day. “Snack eater” was defined as consuming snacks every day.

ALT, alanine aminotransferase; BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; sdLDL-C, small dense low-density lipoprotein cholesterol; SE, staple foods eaters; SS, staple foods skippers