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. 1998 Jul;42(7):1574–1577. doi: 10.1128/aac.42.7.1574

TABLE 6.

β-Lactamase activities of the penicillinase-producing MRSA at different incubation times

Incubation period (h) β-Lactamase activity (mean A482 ± SD)
Control Vancomycin Amoxicillin Co-amoxiclav
0–0.5 0.154 ± 0.005 0.143 ± 0.004 0.146 ± 0.002 0.133 ± 0.009a,b
0.5–2 0.178 ± 0.005 0.139 ± 0.007a 0.134 ± 0.008a 0.119 ± 0.004a,c
2–3 0.203 ± 0.005 0.132 ± 0.007a 0.160 ± 0.009a,d 0.118 ± 0.008a,b
3–6 0.307 ± 0.006 0.116 ± 0.008a 0.178 ± 0.001a,d 0.114 ± 0.002a,b
6–8 0.434 ± 0.006 0.106 ± 0.004a 0.301 ± 0.011a,d 0.109 ± 0.001a,b
a

Statistically significant versus control. 

b

Statistically significant (co-amoxiclav versus amoxicillin). 

c

Statistically significant (co-amoxiclav versus vancomycin). 

d

Statistically significant (amoxicillin versus vancomycin).