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. 2023 Oct 10;13:18. doi: 10.1038/s41387-023-00247-1

Table 3.

Cox regression analysis for comparing the risk of all-cause and cardiovascular mortality between groups of low MIND diet score and high MIND diet score in T2DM and non-DM cohorts.

Model HR (95% CI) P-value1 P-value2
MIND diet score-L/non-DM MIND diet score -H/non-DM MIND diet score -L/DM MIND diet score -H/DM
All-cause mortality
Number of deaths/totals 436/3265 313/2601 214/581 124/440
Crude Ref [1] 0.83 (0.67, 1.03) Ref [2] 0.73 (0.56, 0.95) 0.093 0.020
Model 1 Ref [1] 0.63 (0.53, 0.77) Ref [2] 0.64 (0.50, 0.83) < 0.001 < 0.001
Model 2 Ref [1] 0.83 (0.67, 0.97) Ref [2] 0.76 (0.60, 0.96) 0.021 0.022
Model 3 Ref [1] 0.83 (0.70, 0.99) Ref [2] 0.75 (0.59, 0.96) < 0.001 0.021
Cardiovascular mortality
Number of deaths/totals 143/3265 104/2601 88/581 42/440
Crude Ref [1] 0.83 (0.64, 1.07) Ref [2] 0.47 (0.26, 0.84) 0.146 0.011
Model 1 Ref [1] 0.62 (0.48, 0.81) Ref [2] 0.43 (0.24, 0.78) <0.001 0.005
Model 2 Ref [1] 0.81 (0.60, 1.10) Ref [2] 0.49 (0.28, 0.86) 0.185 0.012
Model 3 Ref [1] 0.85 (0.62, 1.16) Ref [2] 0.50 (0.29, 0.87) 0.309 0.014

Model 1: adjusted for age, sex, and race/ethnicity;

Model 2: further adjusted (from Model 1) for education level, family income to poverty ratio, smoking status, BMI, and physical activity;

Model 3: further adjusted (from Model 2) for hypertension, dyslipidemia, energy intake, and eGFR.

Low MIND score, the MIND score ≤ 8; High MIND score, the MIND score > 8.

HRs Hazard ratios, CIs Confidence intervals, MIND diet Mediterranean-DASH Diet Intervention for Neurodegenerative Delay diet, DM Diabetes mellitus, BMI Body mass index, eGFR Estimated glomerular filtration rate, Ref Reference, P value1: The P value between MIND diet score-Low/non-DM and MIND diet score-High/non-DM groups. P value2: The P value between MIND diet score-Low/DM and MIND diet score-High/DM groups.