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. 2023 Sep 27;13:1250355. doi: 10.3389/fonc.2023.1250355

Table 3.

Univariate and multivariate logistic regression analyses of factors associated with CR achievement after AHSCT.

Variable Univariate Multivariate
OR 95%CI
Lower
95%CI
Upper
p OR 95%CI
Lower
95%CI
Upper
p
CR before AHSCT 23.10 2.53 210.89 0.0054 38.55 3.04 489.24 0.0048
≥2 lines before AHSCT 0.31 0.07 1.27 0.1027
Cytogenetic risk group Unknown Reference
Standard Risk 0.21 0.02 1.90 0.1662
High Risk 1.71 0.22 13.56 0.6094
Maintenance treatment 0.65 0.06 6.72 0.7145
Melphalan dose Mel 200 0.60 0.18 2.01 0.4028
Reduced dose Reference
Induction regimen Bortezomib-based 2.89 0.69 12.02 0.1448
ISS I/II Reference
III 0.25 0.06 1.06 0.0596
Age <60 Reference
>60 0.49 0.15 1.63 0.2438
Paraprotein type Other Reference
LCD 1.00 0.22 4.61 1.0000
hsa-miR-221-3p T1 2.97 0.83 10.59 0.0926
hsa-miR-15b-5p T1 0.78 0.36 1.70 0.5329
hsa-miR-223-3p T1 5.76 1.63 20.28 0.0065 4.72 1.14 19.59 0.0327
hsa-miR-320c T1 0.73 0.26 2.10 0.5647
hsa-miR-361-3p T1 0.82 0.29 2.27 0.6954
hsa-miR-150-5p T1 1.37 0.63 2.98 0.4222
hsa-miR-221-3p T2 3.57 1.09 11.75 0.0362 3.29 0.61 17.76 0.1659
hsa-miR-15b-5p T2 1.18 0.51 2.73 0.6936
hsa-miR-223-3p T2 1.70 0.84 3.44 0.1390
hsa-miR-320c T2 0.76 0.37 1.58 0.4628
hsa-miR-361-3p T2 1.30 0.75 2.26 0.3432
hsa-miR-150-5p T2 0.92 0.48 1.73 0.7903