Table 1.
Relationship between neutrophil/lymphocyte ratio (NLR) levels and changes and patient clinicopathological characteristics.
| Clinical factors | Pre-operative NLR | X² | P | Post-operative NLR | X² | P | NLR changes† | X² | P | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low cohort | High cohort | Low cohort | High cohort | Low cohort | High cohort | |||||||
| Age (years) | ||||||||||||
| <50 | 67 (77.9) | 19 (22.1) | 6.210 | 0.013 | 29 (34.1) | 56 (65.9) | 0.854 | 0.355 | 36 (42.4) | 49 (57.6) | 0.044 | 0.833 |
| ≥50 | 105 (90.5) | 11 (9.5) | 47 (40.5) | 69 (59.5) | >47 (40.9) | 68 (59.1) | ||||||
| Menopausal status | ||||||||||||
| Premenopausal | 78 (76.5) | 24 (23.5) | 12.270 | 0.000 | 37 (36.6) | 64 (63.4) | 0.120 | 0.729 | 49 (48.5) | 52 (51.5) | 4.136 | 0.042 |
| Postmenopausal | 94 (94.0) | 6 (6.0) | 39 (39.0) | 61 (61.0) | 34 (34.3) | 65 (65.7) | ||||||
| Tumor stage | ||||||||||||
| I | 127 (86.4) | 20 (13.6) | 0.663 | 0.416 | 56 (38.1) | 91 (61.9) | 0.019 | 0.891 | 62 (42.5) | 84 (57.5) | 0.208 | 0.649 |
| II | 45 (81.8) | 10 (18.2) | 20 (37.0) | 34 (63.0) | 21 (38.9) | 33 (61.1) | ||||||
| Tumor differentiation | ||||||||||||
| High | 29 (80.5) | 7 (19.5) | 0.641 | 0.423 | 7 (20.0) | 28 (80.0) | 6.255 | 0.012 | 10 (28.6) | 25 (71.4) | 3.523 | 0.061 |
| Moderate-poor | 122 (85.9) | 20 (14.1) | 61 (43.0) | 81 (57.0) | 65 (46.1) | 76 (53.9) | ||||||
| Tumor size (cm) | ||||||||||||
| <2cm | 70 (92.1) | 6 (7.9) | 4.498 | 0.034 | 30 (40.0) | 45 (60.0) | 0.307 | 0.580 | 27 (36.0) | 48 (64.0) | 1.167 | 0.280 |
| ≥2cm | 99 (81.1) | 23 (18.9) | 44 (36.0) | 78 (64.0) | 53 (43.8) | 68 (56.2) | ||||||
| Depth of invasion | ||||||||||||
| <1/2 | 103 (88.0) | 14 (12.0) | 1.831 | 0.176 | 44 (38.3) | 71 (61.7) | 0.023 | 0.879 | 46 (40.0) | 69 (60.0) | 0.251 | 0.617 |
| ≥1/2 | 69 (81.1) | 16 (18.9) | 32 (37.2) | 54 (62.8) | 37 (43.5) | 48 (56.5) | ||||||
| Involvement of the vaginal wall | ||||||||||||
| No | 158 (85.9) | 26 (14.1) | 0.330 | 0.566 | 69 (37.7) | 114 (62.3) | 0.010 | 0.921 | 74 (40.7) | 108 (59.3) | 0.589 | 0.443 |
| Yes | 14 (77.8) | 4 (22.2) | 7 (38.9) | 11 (61.1) | 9 (50.0) | 9 (50.0) | ||||||
| Parietal involvement (of the uterus) | ||||||||||||
| No | 169 (85.4) | 29 (14.6) | 0.477 | 74 (37.6) | 123 (62.4) | 0.000 | 1.000 | 81 (41.3) | 115 (58.7) | 0.000 | 1.000 | |
| Yes | 3 (75.0) | 1 (25.0) | 2 (50.0) | 2 (50.5) | 2 (50.0) | 2 (50.0) | ||||||
| Endothelial involvement | ||||||||||||
| No | 168 (85.3) | 29 (14.7) | 0.556 | 76 (38.8) | 120 (61.2) | 1.687 | 0.194 | 83 (42.6) | 112 (57.4) | 2.096 | 0.148 | |
| Yes | 4 (80.0) | 1 (20.0) | 0 (0.0) | 5 (100.0) | 0 (0.0) | 5 (100.0) | ||||||
| Lymph node metastasis | ||||||||||||
| No | 147 (86.5) | 23 (13.5) | 0.897 | 0.344 | 67 (39.9) | 101 (60.1) | 1.865 | 0.172 | 71 (42.3) | 97 (57.7) | 0.251 | 0.616 |
| Yes | 25 (78.1) | 7 (21.9) | 9 (27.3) | 24 (72.7) | 12 (37.5) | 20 (62.5) | ||||||
| Vascular infiltration | ||||||||||||
| Nos | 138 (88.5) | 18 (11.5) | 5.946 | 0.015 | 58 (37.4) | 97 (62.6) | 0.044 | 0.834 | 56 (36.1) | 99 (63.9) | 8.186 | 0.004 |
| Yes | 34 (73.9) | 12 (26.1) | 18 (39.1) | 28 (61.9) | 27 (60.0) | 18 (40.0) | ||||||
†The postoperative NLR was divided into lower and elevated cohorts relative to the preoperative NLR.
†The bold values represent P-values that are all less than 0.05. The significance level was set at P<0.05.