Time-dependent release of TNF, IL-10, IL-6, IFN-γ, IL-12 p40, and IL-12 p70 in HKSP-stimulated blood. Whole blood diluted 1:1 in sterile RPMI 1640 was stimulated for 4 to 24 h at 37°C with HKSP (•, 107 CFU/ml; ○, 106 CFU/ml). Data are means ± standard errors of the means for six healthy donors.