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. Author manuscript; available in PMC: 2023 Oct 11.
Published in final edited form as: Melanoma Res. 2021 Jun 1;31(3):197–207. doi: 10.1097/CMR.0000000000000734

Figure 4 – Changes to melanocyte migration after exposure to Hsp90i combinations –

Figure 4 –

A) KU75+MAPKi combinations decreased cell migration compared to inhibitors alone and is represented by fewer cells crossing the scratched area (red line). B) The percent of cell migration at 24hrs was calculated with the most significant cell migration (>30%) was observed in untreated, Ve, Cb, and WGA-TA treated cells (p<0.05). All other treatments mitigated cell migration into the scratched areas. C) The number of migrated cells across the membrane were counted. All treatments significantly decreased cell migration compared to untreated (p<0.001). KU758+Ve and KU758+Cb decreased cell migration to a greater extent than each inhibitor alone (p<0.05). XL888+Ve and XL888+Cb exhibited similar decrease (p<0.05).