Table 1.
Baseline characteristics of single and multiple groups
| Variable | Single group (n=81) | Multiple group (n=52) | Total (n=133) | P-value | |
|---|---|---|---|---|---|
| Age | 64 (41-86) | 61 (39-96) | 62 (39-96) | 0.512 | |
| Sex, male | 66 (81.5) | 46 (88.5) | 112 (84.2) | 0.281 | |
| BMI (kg/m2) | 24.30 (17.41-35.79) | 25.46 (18.55-32.77) | 24.60 (17.41-35.79) | 0.907 | |
| Hypertension | 38 (46.9) | 27 (51.9) | 65 (48.9) | 0.573 | |
| Diabetes mellitus | 23 (28.4) | 13 (25.0) | 36 (27.1) | 0.667 | |
| Underlying liver disease | |||||
| HBV | 49 (60.5) | 37 (71.2) | 86 (64.7) | 0.209 | |
| HCV | 5 (6.2) | 6 (11.5) | 11 (8.3) | 0.339 | |
| Alcoholic liver disease | 2 (2.5) | 4 (7.7) | 6 (4.5) | 0.209 | |
| Laboratory finding | |||||
| Hemoglobin | 13.8 (7.7-18.5) | 14.2 (8.6-16.7) | 13.9 (7.7-18.5) | 0.311 | |
| Platelet, ×103 | 176 (33-593) | 162.5 (75-419) | 170 (33-593) | 0.189 | |
| Albumin | 4.1 (2.8-5.0) | 4.2 (3.0-5.1) | 4.1 (2.8-5.1) | 0.702 | |
| Total bilirubin | 0.65 (0.29-1.56) | 0.69 (0.25-1.54) | 0.67 (0.25-1.56) | 0.234 | |
| AST (IU/L) | 37 (17-275) | 39 (17-346) | 39 (17-346) | 0.405 | |
| ALT (IU/L) | 29 (8-1,782) | 37 (11-273) | 31 (8-1,782) | 0.801 | |
| ALP (IU/L) | 91 (31-252) | 89.5 (45-223) | 90 (31-252) | 0.894 | |
| PT (%) | 97 (62-129) | 96 (61-131) | 96 (61-131) | 0.447 | |
| ICG-R15 (%) | 13 (0-86) | 15 (2-31) | 14 (0-86) | 0.949 | |
| MELD score | 7 (6-21) | 8 (6-12) | 7 (6-21) | 0.828 | |
| Child-Pugh score | 1.000 | ||||
| A | 81 (100.0) | 52 (100.0) | 133 (100.0) | ||
| B | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| C | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| Tumor characteristic | |||||
| AFP (ng/mL) | 31 (1-160,907) | 10 (2-378,320) | 24 (1-378,320) | 0.927 | |
| PIVKA-II (mAU/mL) | 646 (0-100,000) | 306 (11-38,277) | 367 (0-100,000) | 0.498 | |
| Tumor size, maximum in image | 5.5 (1.2-22.0) | 4.2 (1.2-16.0) | 4.9 (1.2-22.0) | 0.035 | |
| BCLC stage | <0.001 | ||||
| 0 | 5 (6.2) | 0 (0.0) | 5 (3.8) | ||
| A | 68 (84.0) | 11 (21.2) | 79 (59.4) | ||
| B | 0 (0.0) | 38 (73.1) | 38 (28.6) | ||
| C | 8 (9.9) | 3 (5.8) | 11 (8.3) | ||
Values are presented as median (range) for continuous data and number (%) for categorical data.
BMI, body mass index; HBV, hepatitis B virus; HCV, hepatitis C virus; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; PT, prothrombin time; ICG, indocyanine green; MELD, model for end-stage liver disease; AFP, alpha-fetoprotein; PIVKA-II, protein induced by vitamin K absence-II; BCLC, Barcelona Clinic Liver Cancer.