Figure 3.

Expression of TGF-β decoy receptor does not affect primary T cell differentiation per se

(A) Flow cytometry t-distributed stochastic neighbor embedding (tSNE) analysis of concatenated biological replicates shows a similar differentiation of control and decoy receptor expressing ATCs over time. (B and C) Line graphs of each of the T cell subtypes over time confirm a similar differentiation and proliferation pattern in GPI-ecto-TβRII-positive ATCs compared with WT and GFP control cells. Line graphs display the mean and SEM of 6 biological replicates.