FIG. 3.

Median change in HIV RNA loads (log₁₀ copies per milliliter) after 6 months of adefovir dipivoxil therapy among different groups of patients on the basis of prior AZT experience and presence of AZT resistance mutations at initiation of maintenance-phase adefovir dipivoxil dosing. Other antiretroviral agents were concomitantly used by 50% of the patients. The four patient groups include all patients (n = 28), patients who were AZT naive (n = 7), patients who were AZT experienced but whose viruses had no AZT-associated resistance mutations (n = 7), and patients who were AZT experienced and whose viruses had one or more AZT-associated resistance mutations (n = 14), as indicated by the bars from top to bottom, respectively. Standard error bars are indicated.