1. Outcome all‐cause death and sensitivity analyses.

Analysis	Participants	Nominator	Denominator
Primary analysis (Intention‐to‐treat, best‐case) Sensitivity analysis 1 ‐ best‐case	Lost to follow‐up	Excludeda	Included
Sensitivity analysis 2 ‐ worst‐caseb	Lost to follow‐up	Included as deaths	Included
Observed case analysis (as per trial authors)	Lost to follow‐up	Excluded	Excluded

^a"Excluded" means removed from the calculation.

^bTo re‐classify missing participants (missing data, including losses to follow‐up) as treatment failures. For negative outcomes (death) this represents a true worst‐case scenario.