Date	Event	Description
8 September 2020	New citation required and conclusions have changed	In response to feedback we added a reference to CASTA 2012 for a citation in the 'Discussion', 'Agreements and disagreements with other studies or reviews', and 'Use of statistical instruments' sections of the review, and edited the first sentence of the subsection 'Commercial influences or risks of sponsored science'.
13 November 2019	New search has been performed	Searches updated. Background section revised and updated, and new references added. Searches updated and PRISMA diagram updated. We identified one new study; the review now has seven included studies involving 1601 participants. We edited and updated the text, risk of bias tables, and summary of findings table.
13 November 2019	New citation required but conclusions have not changed	The conclusions have not changed. New author added.
11 April 2017	Amended	In response to feedback, we refined the outcome serious adverse events (SAEs) and replaced it with: total number of people with SAEs; total number of people with fatal SAEs; and total number of people with non‐fatal SAEs.
11 April 2017	New citation required and conclusions have changed	Conclusions changed.
27 May 2016	New citation required and conclusions have changed	The conclusions of the review have changed.
27 May 2016	New search has been performed	We refined the inclusion criteria to allow the inclusion of trials where the length of Cerebrolysin use was not restricted to 14 days (any length of use). We performed a new search and included five new studies. The review now has six included studies involving 1501 participants. Ludivine Vernay joined the author team. We used Covidence for managing records, papers, and trials, to extract data and assess risk of bias, and to resolve conflicting opinions of the authors. We refined the conclusions.
27 January 2015	New citation required but conclusions have not changed	We performed a new search. The conclusions have not changed.
15 July 2008	Amended	Converted to new review format.