TABLE 2.

Concentrations of FLX, PFL, and their metabolites in urine

Collection interval (h)	Mean (range) concn (μg/ml) and na for:
	FLX		FNO		NDF		PFL		NOR		PNO
	n	Concn (range)	n	Concn (range)	n	Concn (range)	n	Concn (range)	n	Concn (range)	n	Concn (range)
preb	0	-c	0	-	0	-	0	-	0	-	0	-
0–6	12	217 (98–427)	12	21.4 (4–70)	12	16.3 (5–40)	12	84.0 (37–219)	12	80.3 (20–144)	12	115.4 (29–233)
6–12	12	160 (63–355)	12	17.6 (4.6–62)	12	16.8 (4–49)	12	50.1 (22–97)	12	76.3 (46.1–133)	12	93.8 (19–192)
12–24	12	102 (43–178)	12	10.2 (5–19)	12	12.2 (5.5–24.5)	11d	46.0 (8–104)	11d	72.9 (31–109)	11d	70.5 (31–115)
24–48	12	26.8 (12–49)	12	2.4 (1.2–5.8)	12	3.1 (0.8–9)	12	19.0 (2.3–53)	12	29.1 (14–68)	12	27.3 (10–70)
48–72	12	6.3 (2.4–11.8)	1	1.5e	8	0.7 (0.7–1.7)	12	5.8 (0.2–13.8)	12	10.2 (1.7–23)	12	8.7 (1.2–19)
72–96	12	2.2 (0.8–3.9)	0	-	2	0.2 (0.9–1.3)	10	2.4 (0.3–8.9)	12	3.9 (0.4–7)	12	3.4 (0.2–12)
96–120	8	0.6 (0.5–1.4)	0	-	0	-	9	0.9 (0.3–3.4)	12	1.5 (0.1–4.4)	10	1.3 (0.1–4.2)
120–144	4	0.3 (0.7–1)	0	-	2	0.1 (0.6–0.8)	8	0.5 (0.2–3.2)	10	0.5 (0.1–2.4)	8	0.5 (0.2–3.7)
144–168	4	0.2 (0.5–0.8)	0	-	1	0.8e	5	0.2 (0.1–2)	8	0.3 (0.1–2)	6	0.3 (0.1–2.8)

^an, number of individuals with concentrations above the quantification limit. 

^bpre, sample taken prior to drug administration. 

^c-, below quantification limit. 

^dOne sample not available. 

^eSince n = 1, the concepts of mean and range are not applicable.