Skip to main content
. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: J Mol Cell Cardiol. 2023 Jul 10;182:1–14. doi: 10.1016/j.yjmcc.2023.06.004

Figure 1. Myocardial microRNA (miRNAs) expression profiles in animals subjected to myocardial ischemia-reperfusion.

Figure 1.

A. Hierarchal clustering heat map showing all differentially expressed microRNAs in WT and APN-KO mice hearts. B. Venn diagram showing 23 miRNAs was the same over-crossed from WT and APN-KO comparation (Up panel). miRNA expression fold change was calculated between WT and APN-KO Sham over MI/R (Down panel). C. Digital PCR validation using miRNA-specific primer assays for miR-449b in cardiac tissues. **p<0.01 versus MI/R, respectively; ##p < 0.01 versus WT-MI/R group. Statistical significance was evaluated by a two-way ANOVA. Post hoc pairwise tests for indicated group pairs were performed after Tukey correction. MI/R, myocardial ischemia/reperfusion.