Table 3.

Serial Changes of Circumpapillary RNFL Thickness and CD Compared to the Baseline Measurements (Negative Pressure = 0 mmHg, N = 24 eyes)

Negative Pressure (mmHg)	RNFL thickness (μm) change (95% CI)	P value*	CD (%) change (95% CI)	P value*
−5	0.07 (−1.36, 1.50)	0.922	0.93 (−0.66, 2.53)	0.251
−10	−1.18 (−2.68, 0.33)	0.126	1.74 (0.07, 3.42)	0.042
−15	−0.86 (−2.39, 0.67)	0.273	1.77 (0.07, 3.48)	0.042
−20	−1.05 (−2.60, 0.51)	0.188	2.27 (0.54, 4.01)	0.010
−15	−0.88 (−2.34, 0.58)	0.238	2.05 (0.41, 3.68)	0.014
−10	0.20 (−1.27, 1.66)	0.793	1.92 (0.29, 3.55)	0.021
−5	−0.40 (−1.89, 1.09)	0.600	0.62 (−1.05, 2.28)	0.468
0	−0.33 (−1.87, 1.21)	0.674	0.38 (−1.33, 2.10)	0.661

RNFL: retinal nerve fiber layer, CD: capillary density.

Linear mixed effects model with repeated measures was used to evaluate the statistical significance.

^*Statistically significant P values (< 0.05) are shown in bold.