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High glucose-induced ferroptosis in SCs. SCs were cultured and treated with eratin and fer-1 combined with high glucose. (a) CCK-8 assay was performed to estimate the cell proliferation viability of SCs. (b) The Ferroptosis-related protein levels of GPX4 and SLC7A11 were determined by western blotting. (c) Real-time PCR analysis of the expression of GPX4. **P < 0.001, ***P < 0.0001.
