TABLE 1.
MICs of tetracyclines for bacterial strains used in this study
| Bacterial strain(s) | MIC (μg/ml)a
|
||
|---|---|---|---|
| TET | DOX | MIN | |
| Susceptible propionibacteria (n = 16) | 0.12–1 | 0.06–0.5 | 0.06–0.5 |
| Resistant propionibacteria (n = 21) | 2–64 | 1–32 | 0.25–4 |
| Lab-generated resistant propionibacteria (n = 6) | 2–8 | 1–4 | 1–2 |
| E. coli(pKK3535) | 2.0 | 2.0 | 1.5 |
| E. coli(pKK1058C-1) | 4.5 | 4.0 | 3.0 |
| E. coli(pKK1058C-2) | 4.5 | 4.0 | 3.0 |
| E. coli(pKK1058C-3) | 4.5 | 4.0 | 3.0 |
a
TET, tetracycline; DOX, doxycycline; MIN, minocycline. MICs for propionibacteria are ranges for all strains tested.