Survival rate of mice with pulmonary cryptococcosis treated with an intravenous injection of 5% dextrose (○), NS-718 (•), conventional AMPH-B (Fungizone) (▵), or liposomal AMPH-B (AmBisome) □ (dose, 2.0 mg of AMPH-B per kg of body weight). Ten mice were used in each group. ∗, ‡, and †, P < 0.05, compared with results for 5% dextrose, Fungizone, and AmBisome, respectively, by generalized Wilcoxon test.