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MICs of antifungal agents for 18 strains of C. neoformans
| Drug | MIC (μg/ml)a
|
||
|---|---|---|---|
| Range | 50% | 90% | |
| AMPH-B | 0.5–2 | 1 | 2 |
| Fungizone | 0.5 | 0.5 | 0.5 |
| AmBisome | 0.25–1 | 0.5 | 1 |
| NS-718 | 0.0313–0.125 | 0.0625 | 0.125 |
The MICs of antifungal agents were determined by the microdilution method modified from the macrodilution method of the National Committee for Clinical Laboratory Standards (19). The 50% and 90% MICs are the MICs at which 50 and 90% of the isolates were inhibited, respectively.
