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. 2023 Oct 4;622(7982):321–328. doi: 10.1038/s41586-023-06600-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a–c, AT is generalizable to different classes of objects, illustrated here for three different general types. a, Assembly pathway to construct diethyl phthalate molecule considering molecular bonds as the building blocks. The figure shows the pathway starting with the irreducible constructs to create the molecule with assembly index 8. b, Assembly pathway of a peptide chain by considering building blocks as strings. Left, four amino acids as building blocks. Middle, the actual object and its representation as a string. Right, assembly pathway to construct the string. c, Generalized assembly pathway of an object comprising discrete components.