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. 2023 Oct 11;13:17218. doi: 10.1038/s41598-023-44316-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of viral E3/49K on cytokine levels of stimulated human PBMC. Human PBMC (1 × 10⁵/well) were stimulated with irradiated L23-control or L23-E3/49K cells (25 × 10³/well). Supernatants of the co-cultures were harvested after 24h and analyzed for levels of IL-2, IL-4, IL-6, IL-10, IFN-γ and TNF-α. The bar graph summarizes means of 3 experiments (concentration; pg/ml). Statistical significance was determined by ANOVA.