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. 2023 Jun 25;2(1):e000339. doi: 10.1136/bmjmed-2022-000339

Table 1.

Linear dose-response meta-analyses of body mass index and mortality outcomes: summary of main results

No of studies No of deaths/total
No of men
Summary hazard ratio (95% CI)
for random effects
Summary hazard ratio (95% CI)
for fixed effects
Heterogeneity Small study effects: Egger’s P value,
Debray’s P value
τ2
I2 (%)
(95% CI)
95% PI Q value, P value
All cause mortality
Linear dose- response meta-analysis
(per 5 unit increase in body mass index)*
25 13811/58 574 0.98 (0.93 to 1.04) 1.02 (0.99 to 1.04) 77 (66 to 84) 0.77 to 1.26 103,<0.01 0.13, 0.49 0.01
Mortality specific to prostate cancer
Linear dose- response meta-analysis
(per 5 unit increase in body mass index)
16 3412/55 457 1.08 (1.00 to 1.17) 1.06 (1.01 to 1.10) 54 (19 to 74) 0.84 to 1.38 33,<0.01 0.23, 0.32 0.01

CI=confidence interval; PI=prediction interval.

*Number of deaths in an included publication was not given or could not be estimated, or both.