Table 1.
No of studies | No of deaths/total No of men |
Summary hazard ratio (95% CI) for random effects |
Summary hazard ratio (95% CI) for fixed effects |
Heterogeneity | Small study effects: Egger’s P value, Debray’s P value |
τ2 | |||
I2 (%) (95% CI) |
95% PI | Q value, P value | |||||||
All cause mortality | |||||||||
Linear dose- response meta-analysis (per 5 unit increase in body mass index)* |
25 | 13811/58 574 | 0.98 (0.93 to 1.04) | 1.02 (0.99 to 1.04) | 77 (66 to 84) | 0.77 to 1.26 | 103,<0.01 | 0.13, 0.49 | 0.01 |
Mortality specific to prostate cancer | |||||||||
Linear dose- response meta-analysis (per 5 unit increase in body mass index) |
16 | 3412/55 457 | 1.08 (1.00 to 1.17) | 1.06 (1.01 to 1.10) | 54 (19 to 74) | 0.84 to 1.38 | 33,<0.01 | 0.23, 0.32 | 0.01 |
CI=confidence interval; PI=prediction interval.
*Number of deaths in an included publication was not given or could not be estimated, or both.