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. 2023 Sep 28;10:1272705. doi: 10.3389/fvets.2023.1272705

Table 2.

Summary of the toxicants confirmed or suspected in 313 dogs and 100 cats treated with intravenous lipid emulsion (ILE).

Toxicant n (dogs) % (dogs) n (cats) % (cats) n (total) % (total)
Total 313 100 100 100 413 100
Unknown 142 45.4 58 58.0 200 48.4
Tremorgenic mycotoxins 43 13.7 43 10.4
Walnut* (penitrem A, roquefortine) 21 6.7 21 5.1
Garbage 11 3.5 11 2.7
Tainted meat/feed 5 1.6 5 1.2
Compost 5 1.6 5 1.2
Other mycotoxin 1 0.3 1 0.2
Rodenticides 12 3.8 21 21.0 33 8.0
Alpha-chloralose 7 2.2 16 16 23 5.6
Coumatetralyl or unknown 4 1.3 4 4.0 8 1.9
Coumarin derivative 1 0.3 1 1.0 2 0.5
Recreational Drugs 28 8.9 2 2.0 30 7.3
Tetrahydrocannabinol (THC)* 18 5.8 2 2.0 20 4.8
Nicotine 9 2.9 9 2.2
Unknown drugs 1 0.3 1 0.2
Plants and plant-based toxins 22 7.0 1 1.0 23 5.5
Cyanogen-Glykosid (Prunus laurocerasus, Phaseolus spp., cherries, mirabelles*) 5 1.6 5 1.2
Grapes/raisins (Vitis ssp.) 4 1.3 4 1.0
Mushroom 3 1.0 3 0.7
Yew berries (Taxus baccata L.) 2 0.6 2 0.5
Lily of the valley (Convallaria majalis) 1 0.3 1 0.2
Beechnuts (Fagus sylvatica) 1 0.3 1 0.2
Unknown plant 1 0.3 1 0.2
Bark mulch 1 0.3 1 0.2
Blue green algae 1 0.3 1 0.2
Rhododendron 1 0.3 1 0.2
Ivy (Hedera helix) 1 0.3 1 0.2
Stagnant water 1 0.3 1 0.2
Monstera deliciosa 1 1.0 1 0.2
Food leftovers/kitchen waste 23 7.3 23 5.5
Theobromine* 11 3.5 11 2.7
Any food leftovers/kitchen waste (e.g., fish) 7 2.2. 7 1.7
Alcohol* 2 0.6 2 0.5
Caffeine* 2 0.6 2 0.5
Xylitol 1 0.3 1 0.2
Chemicals 13 4.2 8 8.0 21 5.1
Fertilizer 5 1.6 1 1.0 6 1.5
Didecyldimethylammonium chloride 5 5.0 5 1.2
Poison baits, incl. Parathion/sulfotep and organophosphates 3 1.0 3 0.7
Chemicals (e.g., heat pad) 2 0.6 1 1.0 3 0.7
Cleaning solution 1 0.3 1 1.0 2 0.5
Glyphosphate herbicide (round-up) 1 0.3 1 0.2
Pen/ink 1 0.3 1 0.2
Antiparasitics 10 3.2 6 6.0 16 3.9
Permethrin 4 4.0 4 1.0
Pyrethrum/Permethrin 3 1.0 3 0.7
Deltamethrin 2 0.6 2 0.5
Ivermectin 2 0.6 2 0.5
Permethrin + pyriproxyfen + dinotefuran 1 1.0 1 0.2
Milbemycin 1 1.0 1 0.2
Moxidectin/Imidacloprid 1 0.3 1 0.2
Fluralaner 1 0.3 1 0.2
Unknown spot-on 1 0.3 1 0.2
Other medication 8 2.6 4 4.0 12 2.9
NSAIDs 3 1.0 2 2.0 5 1.2
Ibuprofen (NSAID) 2 0.6 2 0.5
Robenacoxib (NSAID) 2 2.0 2 0.5
Diclofenac (NSAID) 1 0.3 1 0.2
Anticonvulsants 1 0.3 1 0.3
Phenobarbital/Potassium bromide/Imepetoin 1 0.3 1 0.3
Other 4 12 1
Metronidazole 1 0.3 1 0.2
Clozapine* 1 0.3 1 0.2
5-Hydroxytryptophan 1 0.3 1 0.2
Lisdexamfetamin 1 1.0 1 0.2
DL-mehtionine 1 1.0 1 0.2
Unknown medication 1 0.3 1 0.2
Feces/manure 10 3.2 10 2.4
Nuts 6 1.9 6 1.5
Macadamia nuts 4 1.3 4 1.0
Unknown nuts* 2 0.6 2 0.5
Molluscicides 5 1.6 5 1.2
Metaldehyde 5 1.6 5 1.2

n, number ILE-treated dogs or cats or all patients assigned to at least one of the respective toxicant groups. *Combinations of different toxicant groups or several toxicants within the same toxicant group are possible.