Table 4.
Clinicopathologic findings (hematology, clinical chemistry) in 313 dogs with confirmed or suspected poisoning before (i) and after (ii) intravenous lipid emulsion (ILE) treatment.
| Parameter (unit) | Reference interval | Before ILE | After ILE | ||
|---|---|---|---|---|---|
| n i | Mediani (range) | n ii | Medianii (range) | ||
| HCT (%) | 37,3–61,7 | 273 (87.2%) | 48.2 (17.6–68.7) | 17 (5.4%) | 40.6 (14.5–547) |
| WBC (×109/L) | 5,05–16,76 | 272 (86.9%) | 10.8 (2.02–30.31) | 12 (3.8%) | 9.3 (5.26–16.68) |
| Plt (×109/L) | 148–484 | 272 (86.9%) | 269 (35–619) | 12 (3.8%) | 202 (68–403) |
| TP (g/L) | 53.0–74.0 | 260 (83.7%) | 64.0 (39.0–110.0) | 6 (1.9%) | 50.5 (40.4–68.0) |
| Alb (g/L) | 30.9–45.0 | 264 (84.3%) | 36.8 (21.0–80.0) | 9 (2.9%) | 31.5 (20.4–38.0) |
| Crea (μmol/L) | 0–140 | 274 (87.5%) | 84 (23–731) | 22 (7.0%) | 82 (42–741) |
| Urea (mmol/L) | 2.8–8.2 | 265 (84.7%) | 6.7 (1.8–50.0) | 17 (5.4%) | 4.5 (1.8–60.0) |
| Glu (mmol/L) | 4.2–6.3 | 274 (87.5%) | 6.1 (2.9–18.1) | 21 (6.7%) | 6.1 (3.6–7.8) |
| AST (nkat/L) | 0–47 | 14 (4.5%) | 31 (10–252) | – | – |
| ALT (U/L) | 0–97 | 260 (83.1%) | 45 (15–405) | 6 (1.9%) | 50 (41–173) |
| AP (U/L) | 0–83 | 199 (63.6%) | 50 (7–634) | 4 (1.3%) | 209 (125–589) |
| Bili (μmol/L) | 0–3.4 | 130 (41.5%) | 1.3 (0–33.2) | 4 (1.3%) | 8.6 (1.8–12.4) |
| Trig (mmol/L) | 0.61–1.07 | 10 (3.2%) | 0.48 (0.31–8.31) | – | – |
| Na (mmol/L) | 143–153 | 257 (82.1%) | 147 (122–169) | 24 (7.7%) | 145 (140–176) |
| K (mmol/L) | 3.9–5.7 | 263 (84.0%) | 4.1 (2.1–6.4) | 23 (7.3%) | 3.9 (2.7–6.7) |
| Cl (mmol/L) | 99–113 | 257 (82.1%) | 112 (90–156) | 23 (7.3%) | 113 (100–137) |
| Ca (mmol/L) | 2.4–2.9 | 171 (54.6%) | 2.8 (2.0–3.5) | 6 (1.9%) | 2.6 (2.3–2.7) |
| Ca++ (mmol/L) | 1.12–1.4 | 3 (1.0%) | 1.43 (1.37–1.45) | – | – |
n, number of dogs or cats (of all 313 dogs or 100 cats in the study, respectively) in which the respective parameter was recorded. TP, total protein concentration; Alb, albumin concentration; Crea, creatinine concentration; Urea, urea concentration; Glu, glucose concentration; AST, aspartate aminotransferase activity; ALT, alanine aminotransferase activity; AP, alkaline phosphatase activity; Bili, bilirubin concentration; Trig, triglyceride; Na, sodium concentration; K, potassium concentration; Cl, chloride concentration; Ca, calcium concentration; Ca++, ionized calcium concentration.