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. 2023 Sep 28;10:1272705. doi: 10.3389/fvets.2023.1272705

Table 7.

Adverse effects of intravenous lipid emulsion (ILE) in 20/313 dogs (6.4%) and 4/100 cats (4.0%) to treat confirmed and suspected poisoning.

Adverse effect n Adverse effect ILE associated Amount of ILE (mL/kg) Outcome
Dogs Loss of consciousness 6 Very probable (6)a,b,c,d 15.0 (2.0–66.6) Survived
Hyperthermia 3 Possible (3)e,f,g 5.9 (8.0–30.0) Survived
Vomiting 3 Very probable (3)a,c,h 30.3 (2.2–66.6) Survived
Diarrhea 3 Possible (2)a,i Very probable (1)j 30.3 (11.9–31.5) Survived
Reduced level of consciousness 2 Possible (2)j,k 9.0; 15.0 Survived
Bradycardia 2 Very probable (1)l Possible (1)m 9.4; 11.5 Survived
Apnea/Dyspnea 2 Possible (2)a 5.1; 15.0 Euthanized (1) survived (1)
Reduced/worsening of general behavior 3 Very probable (2)a,n Possible (1)a 16.2 (11.5–30.3) Survived
Facial swelling, suspicion of an allergic reaction 1 Very probablea 2.0 Survived
Ataxia 1 Very probablea 30.3 Survived
Cats Tachypnea 1 Very probablea 47.5 Survived
Thrombophlebitis 1 Very probableo 15.8 Survived
Semicomatose state 1 Very probablep 2.0 Survived
Somnolence 1 Very probablea 11.9 Survived
Bradycardia 1 Very probablea 11.9 Survived
Total 24 11.88 (2.0–66.6) Survived (23) euthanized (1)
a

Unknown toxicant (n = 11).

b

Chemical (pen, ink; n = 1).

c

Plant and plant-based toxin (grapes/Vitis sp.; n = 2).

d

food leftovers/kitchen waste (meat and onions; n = 1).

e

Potentially tremorgenic mycotoxins (garbage; n = 1).

f

Recreational Drug (nicotine; n = 1).

g

Food leftovers/kitchen waste (caffeine; n = 1).

h

Food leftovers/kitchen waste (meat and onions; n = 1).

i

Other medication (diclofenac; n = 1).

j

Recreational Drug (THC = tetrahydrocannabinol; n = 1).

k

Nuts (macadamia nuts; n = 1).

l

Food leftovers/kitchen waste (sausage and cherries; n = 1).

m

Antiparasitic (permethrin; n = 1).

n

Rodenticides (coumarine derivative; n = 1).

o

Rodenticides (α-chloralose; n = 1).

p

Rodenticides (unknown rodenticide; n = 1).

n, numbers of animals with the respective adverse effect.