Fig. 3.

Classification of MSCs-EV

(1). EVs are frequently classified and divided into three subgroups, apoptotic bodies (50–5000 nm), microvesicles (100–1000 nm), and exosomes (30–150 nm).

(2). CD9, CD63, CD81, TSG101, and Alix are specific markers of exosomes.

(3). Exosomes carry miRNA, proteins, lipids and grow factors that play an important regulatory role in intercellular communication and signal transduction.