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. 2023 Oct 11;81(1):77–88. doi: 10.1001/jamapsychiatry.2023.3850

Table. Characteristics of the Sample at Clinical High Risk for Psychosis.

Characteristic Participants
All individuals with CHR-P (n = 1340)
Age, mean (SD), y 20.75 (4.74)
Sex, No. (%)
Female 631 (47.09)
Male 709 (52.91)
SIPS positive symptoms score, mean (SD)a,b 10.93 (4.66)
CAARMS positive symptoms score, mean (SD)a,c 10.37 (4.03)
IQ, mean (SD) z scored −0.21 (1.00)
Prescribed antipsychotic medication, No. (%)e 243 (18.63)
Follow-up, mean (SD), mof 19.71 (13.97)
Individuals who converted to a psychotic disorder, No. (%)f 157 (14.31)
Individuals with CHR-P who converted to a psychotic disorder (n = 157)
Age, mean (SD), y 20.09 (4.68)
Sex, No. (%)
Female 64 (40.76)
Male 93 (59.24)
SIPS positive symptoms score, mean (SD)g 12.12 (5.06)
CAARMS positive symptoms score, mean (SD)h 10.71 (4.24)
IQ, mean (SD) z scorei −0.29 (1.03)
Prescribed antipsychotic medication, No. (%)j 32 (20.38)

Abbreviations: CAARMS, Comprehensive Assessment of At-Risk Mental States; CHR-P, clinical high risk for psychosis; SIPS, Structured Interview for Psychosis-Risk Syndromes.

a

Positive symptom ratings at the time of scanning were available for the entire sample of individuals with CHR-P (n = 1340), assessed either with the SIPS or the CAARMS.

b

The SIPS was used to assess positive symptoms in 806 participants with CHR-P.

c

The CAARMS was used to assess positive symptoms in 534 participants with CHR-P.

d

Estimates of IQ were available for 924 participants with CHR-P; z scores were used to accommodate site differences in the instruments used (eTable 1 in Supplement 1).

e

Medication status at the time of scanning was available for 1304 individuals with CHR-P.

f

Conversion status was known for 1097 participants with CHR-P, but information about the length of the follow-up period was available for only 975 individuals with CHR-P.

g

The SIPS was used to assess 115 individuals with CHR-P who converted to a psychotic disorder.

h

The CAARMS was used to assess 42 individuals with CHR-P who converted to a psychotic disorder.

i

Estimates of IQ were available for 109 individuals with CHR-P who converted to a psychotic disorder.

j

Medication status was available for 157 individuals with CHR-P who converted to a psychotic disorder.