Table. Characteristics of the Sample at Clinical High Risk for Psychosis.
Characteristic | Participants |
---|---|
All individuals with CHR-P (n = 1340) | |
Age, mean (SD), y | 20.75 (4.74) |
Sex, No. (%) | |
Female | 631 (47.09) |
Male | 709 (52.91) |
SIPS positive symptoms score, mean (SD)a,b | 10.93 (4.66) |
CAARMS positive symptoms score, mean (SD)a,c | 10.37 (4.03) |
IQ, mean (SD) z scored | −0.21 (1.00) |
Prescribed antipsychotic medication, No. (%)e | 243 (18.63) |
Follow-up, mean (SD), mof | 19.71 (13.97) |
Individuals who converted to a psychotic disorder, No. (%)f | 157 (14.31) |
Individuals with CHR-P who converted to a psychotic disorder (n = 157) | |
Age, mean (SD), y | 20.09 (4.68) |
Sex, No. (%) | |
Female | 64 (40.76) |
Male | 93 (59.24) |
SIPS positive symptoms score, mean (SD)g | 12.12 (5.06) |
CAARMS positive symptoms score, mean (SD)h | 10.71 (4.24) |
IQ, mean (SD) z scorei | −0.29 (1.03) |
Prescribed antipsychotic medication, No. (%)j | 32 (20.38) |
Abbreviations: CAARMS, Comprehensive Assessment of At-Risk Mental States; CHR-P, clinical high risk for psychosis; SIPS, Structured Interview for Psychosis-Risk Syndromes.
Positive symptom ratings at the time of scanning were available for the entire sample of individuals with CHR-P (n = 1340), assessed either with the SIPS or the CAARMS.
The SIPS was used to assess positive symptoms in 806 participants with CHR-P.
The CAARMS was used to assess positive symptoms in 534 participants with CHR-P.
Estimates of IQ were available for 924 participants with CHR-P; z scores were used to accommodate site differences in the instruments used (eTable 1 in Supplement 1).
Medication status at the time of scanning was available for 1304 individuals with CHR-P.
Conversion status was known for 1097 participants with CHR-P, but information about the length of the follow-up period was available for only 975 individuals with CHR-P.
The SIPS was used to assess 115 individuals with CHR-P who converted to a psychotic disorder.
The CAARMS was used to assess 42 individuals with CHR-P who converted to a psychotic disorder.
Estimates of IQ were available for 109 individuals with CHR-P who converted to a psychotic disorder.
Medication status was available for 157 individuals with CHR-P who converted to a psychotic disorder.