TABLE 1.
The summary of the meta-regression analysis.
| Ursolic acid treat lesions (animal studies) | Ursolic acid treat lesions (in vitro) | |||||
|---|---|---|---|---|---|---|
| Dependent variable | Meta-regression parameter (p-value) | Dependent variable | Meta-regression parameter (p-value) | |||
| Dosage (mg/kg) | Duration (d) | Intervention | Dosage (μM) | Duration (h) | ||
| IL-1β | 0.026 | 0.788 | 0.342 | IL-1β | 0.760 | <0.0001 |
| MDA | 0.462 | 0.616 | 0.662 | IL-6 | 0.169 | 0.295 |
| TNF-α | 0.857 | 0.339 | 0.637 | IL-8 | 0.004 | 0.094 |
| SOD | 0.583 | 0.002 | 0.265 | TNF-α | 0.945 | 0.395 |
Abbreviations: IL-1β, interleukin-1beta; MDA, malondialdehyde; TNF-α, tumor necrosis factor-alpha; SOD, superoxide dismutase; IL-6, interleukin-6; IL-8, interleukin-8.