TABLE 3.
The summary of Egger’s tests.
| Parameter | Egger’s test | |||||
|---|---|---|---|---|---|---|
| Ursolic acid (in vitro) | Ursolic acid treat lesions (animal studies) | Ursolic acid treat lesions (in vitro) | ||||
| t | p-value | t | p-value | t | p-value | |
| IL-1β | 7.83 | 0.080 | −6.85 | <0.0001 | −13.5 | <0.0001 |
| IL-6 | 0.19 | 0.869 | −8.25 | 0.0004 | −7.45 | <0.0001 |
| MDA | −5.79 | < 0.0001 | −2.93 | 0.022 | ||
| SOD | 10.74 | < 0.0001 | 0.28 | 0.789 | ||
| TNF-α | −6.76 | < 0.0001 | −4.62 | 0.0003 | ||
| GSH | 13.84 | 0.0008 | 2.95 | 0.098 | ||
| GPx | — | — | — | — | −0.54 | 0.604 |
| CAT | — | — | — | — | 1.06 | 0.326 |
| IL-10 | — | — | — | — | 120.58 | 0.005 |
| IL-8 | — | — | — | — | −70.81 | <0.0001 |
Abbreviations: IL-1β, interleukin-1beta; IL-6, interleukin-6; MDA, malondialdehyde; SOD, su-peroxide dismutase; TNF-α, tumor necrosis factor-alpha; GPx, glutathione peroxidase; CAT, catalase; IL-10, interleukin-10; GSH, glutathione; IL-8, interleukin-8.