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. 2023 Oct 1;8(40):36614–36627. doi: 10.1021/acsomega.3c02837

Figure 3.

Figure 3

Fibronectin expression in ovarian cancer patients during chemotherapy. (a) Atomic force microscopic view of ovarian ascite fluid exosomes. (b) Western blot analysis of EV marker: (1) ovarian tumor cells derive EVs and (2) ovarian ascite fluid EVs. (c) Fibronectin expression analysis via Western blot ovarian ascite fluid. (d) Fibronectin expression analysis via Western blot tumor cell lysates. (e) Fibronectin expression analysis via a Western blot patient sample. (f) Fibronectin expression pattern before and after chemotherapy in the clinical sample. Fibronectin is one of the key molecular cargos of EVs that lead to the remodeling of the extracellular matrix (ECM). Adapted with permission from ref (59). Copyright 2021. Molecular Oncology published by John Wiley & Sons Ltd.