TABLE 1.

Data of Lipinski rule.

Ligand no.	Molecular weight	Number of rotatable bonds	Hydrogen bond acceptor	Hydrogen bond donor	Topological polar surface area Å2	Consensus Log p o/w	Lipinski rule		Bioavailability score
							Result	Violation
Ligand 01	245.23	2	5	1	64.72	2.24	Yes	0	0.55
Ligand 02	321.33	4	5	1	64.72	3.49	Yes	0	0.55
Ligand 03	369.37	4	5	1	64.72	4.66	Yes	0	0.55
Ligand 04	275.21	3	7	2	102.02	1.78	Yes	0	0.56
Ligand 05	305.2	4	9	3	139.32	1.33	Yes	0	0.56
Ligand 06	259.21	3	6	1	81.79	1.92	Yes	0	0.55
Ligand 07	273.2	4	7	1	98.86	1.57	Yes	0	0.55
Ligand 08	249.19	2	6	1	64.72	2.41	Yes	0	0.55
Ligand 09	253.16	2	7	1	64.72	2.55	Yes	0	0.55