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. 2023 Sep 13;17(19):18979–18999. doi: 10.1021/acsnano.3c04564

Figure 3.

Figure 3

Photothermal properties of Ce6-loaded LUMSNs. (a–e) Temperature increases following NIR laser irradiation (0.5–1.5 W/cm2, 5 min) of Ce6-LUMSNs at nanosphere concentrations of 10 (a), 25 (b), 75 (c), 150 (d), and 200 μg/mL (e), in 10 mM phosphate buffer (pH 7.4). (f) Comparison of NIR laser light (1.0 W/cm2, 10 min)-induced temperature increases in Ce6 and Ce6-LUMSN samples (33 μg/mL Ce6) in 10 mM phosphate buffer (pH 7.4). (g) Thermal images of saline, Ce6, and Ce6-LUMSN (33 μg/mL Ce6) samples illuminated with NIR laser light (1.5 W/cm2) for 5 min. (h) Photothermal response profile of Ce6-LUMSNs (150 μg/mL nanospheres) subjected to NIR laser irradiation (1.5 W/cm2, 10 min) followed by natural cooling. (i) Photothermal stability of Ce6-LUMSNs (150 μg/mL nanospheres) monitored over five consecutive NIR laser irradiation (1.5 W/cm2, 5 min) on/off cycles. *P < 0.05, ***P < 0.001 for comparisons with controls or among the different samples.