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. 2023 Feb 1;62(18):2715–2724. doi: 10.2169/internalmedicine.1178-22

Table 2.

Clinical Characteristics and Recovery Duration of Our Reviewed Patients. The Recovery Day of Thrombocytopenia in Case 11 Is Described as “NA” (*) because the Platelet Count Remained above 10×104/μL throughout the Entire Hospitalization Period. These Data are Not Included in the Analysis.

Case Race Age/ Sex TAFRO grade Critical complications before remission Infections Treatment CRP <1.0mg/dL (day) AKI improved (day) PLT >105 /L (day) Reference
without critical complications 1 Japanese 51 F 2 None NA mPSL pulse, PSL 20 10 40 6
2 Japanese 38 M 3 None NA mPSL pulse, PSL, CsA, TCZ 15 33 38 7
3 Japanese 85 F 3 None NA PSL 12 15 40 8
4 Japanese 76 F 4 None NA PSL 32 49 70 9
5 Japanese 46 M 4 None NA mPSL pulse, PSL, TCZ 25 34 36 10
6 Chinese 52 F 4 None Pneumonia before remission (unknown etiology) mPSL, PSL, BOR, CPA, DEX 25 20 44 11
7 Japanese 69 M 4 None CMV, cholecystitis after remission (unknown etiology), Mycobacterium tuberculosis after remission mPSL pulse, PSL, CsA 40 45 175 12
8 Japanese 48 F 4 None NA mPSL pulse, PSL, TCZ, CsA 20 21 51 13
9 Japanese 60 M 5 None CMV, BK virus mPSL pulse, PSL, TCZ, CsA 18 39 169 Our case
with critical complications 10 Japanese 68 F 2 Septic shock Staphylococcus aureus PSL, TCZ, CsA, TAC 131 221 120 14
11 Japanese 17 M 3 Cardiogenic shock NA mPSL pulse, PSL, TAC 6 3 NA 14
12 Japanese 72 M 5 Cardiac arrest Corynebacterium mPSL pulse, PSL, TCA, CPA 28 120 140 15
13 Japanese 59 M 5 Cardiac arrest NA mPSL pulse, PSL, TCZ, CsA 23 37 88 16
14 Japanese 25 M 5 Cardiac arrest NA PSL, CPA, TCZ 49 76 75 17
15 Japanese 59 M 5 Hemorrhagic shock Pneumocystis jirovecii, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Clostridium difficile, Escherichia coli, CMV, Candida mPSL pulse, PSL, TCZ 166 228 215 18

AKI: acute kidney injury, PLT: platelet, CMV: cytomegalovirus, mPSL: methyl prednisolone, PSL: prednisolone, CsA: ciclosporin, TCZ: tocilizumab, BOR: bortezomib, CPA: cyclophosphamide, DEX: dexamethasone