Table 2.
Case | Race | Age/ Sex | TAFRO grade | Critical complications before remission | Infections | Treatment | CRP <1.0mg/dL (day) | AKI improved (day) | PLT >105 /L (day) | Reference | |
---|---|---|---|---|---|---|---|---|---|---|---|
without critical complications | 1 | Japanese | 51 F | 2 | None | NA | mPSL pulse, PSL | 20 | 10 | 40 | 6 |
2 | Japanese | 38 M | 3 | None | NA | mPSL pulse, PSL, CsA, TCZ | 15 | 33 | 38 | 7 | |
3 | Japanese | 85 F | 3 | None | NA | PSL | 12 | 15 | 40 | 8 | |
4 | Japanese | 76 F | 4 | None | NA | PSL | 32 | 49 | 70 | 9 | |
5 | Japanese | 46 M | 4 | None | NA | mPSL pulse, PSL, TCZ | 25 | 34 | 36 | 10 | |
6 | Chinese | 52 F | 4 | None | Pneumonia before remission (unknown etiology) | mPSL, PSL, BOR, CPA, DEX | 25 | 20 | 44 | 11 | |
7 | Japanese | 69 M | 4 | None | CMV, cholecystitis after remission (unknown etiology), Mycobacterium tuberculosis after remission | mPSL pulse, PSL, CsA | 40 | 45 | 175 | 12 | |
8 | Japanese | 48 F | 4 | None | NA | mPSL pulse, PSL, TCZ, CsA | 20 | 21 | 51 | 13 | |
9 | Japanese | 60 M | 5 | None | CMV, BK virus | mPSL pulse, PSL, TCZ, CsA | 18 | 39 | 169 | Our case | |
with critical complications | 10 | Japanese | 68 F | 2 | Septic shock | Staphylococcus aureus | PSL, TCZ, CsA, TAC | 131 | 221 | 120 | 14 |
11 | Japanese | 17 M | 3 | Cardiogenic shock | NA | mPSL pulse, PSL, TAC | 6 | 3 | NA | 14 | |
12 | Japanese | 72 M | 5 | Cardiac arrest | Corynebacterium | mPSL pulse, PSL, TCA, CPA | 28 | 120 | 140 | 15 | |
13 | Japanese | 59 M | 5 | Cardiac arrest | NA | mPSL pulse, PSL, TCZ, CsA | 23 | 37 | 88 | 16 | |
14 | Japanese | 25 M | 5 | Cardiac arrest | NA | PSL, CPA, TCZ | 49 | 76 | 75 | 17 | |
15 | Japanese | 59 M | 5 | Hemorrhagic shock | Pneumocystis jirovecii, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Clostridium difficile, Escherichia coli, CMV, Candida | mPSL pulse, PSL, TCZ | 166 | 228 | 215 | 18 |
AKI: acute kidney injury, PLT: platelet, CMV: cytomegalovirus, mPSL: methyl prednisolone, PSL: prednisolone, CsA: ciclosporin, TCZ: tocilizumab, BOR: bortezomib, CPA: cyclophosphamide, DEX: dexamethasone