Table 3.
Case | Age/sex | TAFRO grade | Renal biopsy | RRT duration (day) | AKI improved (day) | AKI recovery definition (#) | Creatinine before the onset of TAFRO syndrome | Creatinine on admission | Max creatinine after treatment | Minimum creatinine after treatment | Creatinine at dischage | AKI to CKD | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
without critical complications | 1 | 51 F | 2 | Acute phase | None | 10 | 1 | NA | 1 | 1.2 | 0.6 | 0.8 | Unidentified |
2 | 38 M | 3 | No | 31 | 33 | 2 | NA | 2.8 | 5.0 | 0.8 | 0.8 | Unidentified | |
3 | 85 F | 3 | No | None | 15 | 1 | NA | 1.1 | 1.6 | 0.8 | 1.2 | Probably yes * | |
4 | 76 F | 4 | Chronic phase | 40 | 49 | 2 | NA | 3.0 | 6.5 | 1.4 | 1.5 | Probably yes * | |
5 | 46 M | 4 | No | None | 34 | 1 | NA | 0.9 | 1.5 | 0.9 | 0.9 | Unidentified | |
6 | 52 F | 4 | No | 13 | 20 | 2 | NA | 1.9 | 7.2 | 0.4 | 0.5 | Unidentified | |
7 | 69 M | 4 | Chronic phase | 17 | 45 | 2 | NA | 2.2 | 4.3 | 1.2 | 1.7 | Probably yes * | |
8 | 48 F | 4 | Acute phase | 17 | 21 | 2 | NA | 1.3 | 4.2 | 0.6 | 0.6 | Unidentified | |
9 (Our case) | 60 M | 5 | No | 39 | 39 | 2 | 0.8 | 2.8 | 10.4 | 1.1 | 1.2 | Yes | |
with critical complications | 10 | 68 F | 2 | No | None | 221 | 1 | NA | 1.6 | 1.5 | 0.7 | 0.7 | Unidentified |
11 | 17 M | 3 | No | None | 3 | 1 | NA | 1.6 | 2.7 | 0.6 | 0.8 | Unidentified | |
12 | 72 M | 5 | No | 106 | 120 | 2 | NA | 1.3 | 6.0 | 0.9 | 1.5 | Probably yes * | |
13 | 59 M | 5 | No | 19 | 37 | 2 | NA | 1.3 | 2.2 | 0.9 | 1 | Unidentified | |
14 | 25 M | 5 | No | 76 | 76 | 2 | NA | 1.0 | 4.2 | 0.8 | 0.8 | Unidentified | |
15 | 59 M | 5 | No | 151 | 228 | 2 | NA | 1.4 | 4.5 | 0.8 | 1 | Unidentified | |
Dialysis duration | Cre on admission | Maximum Cre | Cre at discharge | ||||||||||
All patients | 35 [18-67] | 1.4 [1.2-2.1] | 4.2 [1.9-5.5] | 0.9 [0.8-1.2] | |||||||||
Patients without critical complications median [interquartile range, 25-75%] | 24 [17-37] | 1.9 [1.1-2.8] | 4.3 [1.6-6.5] | 0.9 [0.8-1.2] |
The cases described as “probably Yes” (*) have no record of creatinine before the onset of TAFRO syndrome. The AKI recovery definition (#) is shown in Fig. 4b.
RRT: renal replacement therapy, AKI: acute kidney injury, CKD: chronic kidney disease, Cre: creatinine