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. 2023 Feb 1;62(18):2715–2724. doi: 10.2169/internalmedicine.1178-22

Table 3.

Trends in the Renal Function in Our Reviewed Patients.

  Case Age/sex TAFRO grade Renal biopsy RRT duration (day) AKI improved (day) AKI recovery definition (#) Creatinine before the onset of TAFRO syndrome Creatinine on admission Max creatinine after treatment Minimum creatinine after treatment Creatinine at dischage AKI to CKD
without critical complications 1 51 F 2 Acute phase None 10 1 NA 1 1.2 0.6 0.8 Unidentified
2 38 M 3 No 31 33 2 NA 2.8 5.0 0.8 0.8 Unidentified
3 85 F 3 No None 15 1 NA 1.1 1.6 0.8 1.2 Probably yes *
4 76 F 4 Chronic phase 40 49 2 NA 3.0 6.5 1.4 1.5 Probably yes *
5 46 M 4 No None 34 1 NA 0.9 1.5 0.9 0.9 Unidentified
6 52 F 4 No 13 20 2 NA 1.9 7.2 0.4 0.5 Unidentified
7 69 M 4 Chronic phase 17 45 2 NA 2.2 4.3 1.2 1.7 Probably yes *
8 48 F 4 Acute phase 17 21 2 NA 1.3 4.2 0.6 0.6 Unidentified
9 (Our case) 60 M 5 No 39 39 2 0.8 2.8 10.4 1.1 1.2 Yes
with critical complications 10 68 F 2 No None 221 1 NA 1.6 1.5 0.7 0.7 Unidentified
11 17 M 3 No None 3 1 NA 1.6 2.7 0.6 0.8 Unidentified
12 72 M 5 No 106 120 2 NA 1.3 6.0 0.9 1.5 Probably yes *
13 59 M 5 No 19 37 2 NA 1.3 2.2 0.9 1 Unidentified
14 25 M 5 No 76 76 2 NA 1.0 4.2 0.8 0.8 Unidentified
15 59 M 5 No 151 228 2 NA 1.4 4.5 0.8 1 Unidentified
Dialysis duration Cre on admission Maximum Cre Cre at discharge
All patients 35 [18-67] 1.4 [1.2-2.1] 4.2 [1.9-5.5] 0.9 [0.8-1.2]
Patients without critical complications median [interquartile range, 25-75%] 24 [17-37] 1.9 [1.1-2.8] 4.3 [1.6-6.5] 0.9 [0.8-1.2]

The cases described as “probably Yes” (*) have no record of creatinine before the onset of TAFRO syndrome. The AKI recovery definition (#) is shown in Fig. 4b.

RRT: renal replacement therapy, AKI: acute kidney injury, CKD: chronic kidney disease, Cre: creatinine