Figure 3.
The relative abundance of Prevotella copri was higher in the healthy people compared with sarcopenia patients. (A, B) Phylum‐level (A) and genus‐level (B) taxonomic distribution of the gut microbiome among healthy older people and sarcopenia patients on average. (C) LDA scores of the differentially abundant taxa in gut microbiome from healthy people and sarcopenia patients (taxa with LDA score >2 and a significance of a < 0.05 are shown). (D) Cladogram, generated from LEfSe analysis, represented gut microbiome taxa enriched in healthy people and sarcopenia patients. The central point represents the root of the tree (bacteria), and each ring represents the next lower taxonomic level (phylum to genus). (E) Boxplot with notch showed the relative abundance of P. copri . Boxes represent the IQRs between the first and third quartiles, and the line inside the box represents the median. (F) Functional enrichment (KEGG) analysis showed the differential gene contact between healthy older people and SAR patients were enriched in valine, leucine, and isoleucine biosynthesis and fatty acid degradation pathways. *P < 0.05; **P < 0.01; Wilcoxon rank‐sum test.