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. 2023 Jul 12;14(5):2152–2167. doi: 10.1002/jcsm.13292

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© 2023 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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scRNAseq reveals communications between FAPs and other cell types in Wagyu muscle. (A) Cell–cell communication networks include all identified significant communications between different cell types in individual breeds identified by scRNAseq. (B) A heatmap shows the differential cell–cell communications in which FAP‐1 or FAP‐2 functions as the sender between Wagyu and Brahman. The red box highlights VEGF signalling communications from FAPs to EndoCs only detected in Wagyu. The blue box highlights DAG1 signalling communications from FAPs to MCs only detected in Brahman. Values are the ratios of communication probability scores in Wagyu to those in Brahman.