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. 2023 Jul 12;14(5):2152–2167. doi: 10.1002/jcsm.13292

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© 2023 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Bovine FAPs are a heterogeneous population. (A) UMAP graphs show unsupervised clustering of bovine FAPs from all breeds identified by scRNAseq. (B) A dot plot shows the expression of select DEGs among FAP subpopulations. (C) Graphs show the enrichment of select GOBP and Wikipathways terms in FAP C3 and C4. (D) RNA velocity graphs in which different FAPs subpopulations or FAPs of different breeds are differentially labelled. (E) Feature plots show select DEGs among FAP subpopulations. (F) A GRN regulates the differential gene expression among FAP clusters.