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. 2023 Aug 30;16(6):641–653. doi: 10.1007/s40271-023-00643-w

Table 4.

MAR values calculated based on DCE average estimates, individual estimates, and PTT

DCE: mean estimates DCE: individual estimates PTT
Mean (SE) 95% CI Mean (SE) 95% CI Mean (SE) 95% CI
MAR: 40% point RA risk reduction
 Chance of mild side effectsa 50.8 (8.2) 34.7;66.8 42.6 (23.1) −2.7;87.8 18.1 (0.9) 16.3;19.9
 Chance of serious infection 14.0 (1.6) 10.9;17.1 20.6 (25.2) −28.9;70.1 10.2 (0.7) 8.9;11.6
 Chance of serious side effectsa 1.2 (0.4) 0.5;2.0 2.2 (1.2) −0.2;4.5 1.4 (0.3) 0.8; 2.0

CI confidence interval, DCE discrete choice experiment, MAR maximum acceptable risk, PTT probabilistic threshold technique, SE standard error

aThese attributes were effects coded, linearity was assumed between levels and extrapolated beyond the levels included in the DCE for the purpose of the MAR calculation