Table 5.
MAR values from the PTT based on interval regression including relevant covariates and MAR values from the DCE based on a subgroup analysis for significant covariates from the PTT interval regression
| Chance of mild side effects | Chance of serious infection | Chance of serious side effects | ||||||
|---|---|---|---|---|---|---|---|---|
| Mean (SE) | 95% CI | Mean (SE) | 95% CI | Mean (SE) | 95% CI | |||
| PTT estimates | ||||||||
| Mean MAR (intercept) | 17.1 (1.3)*** | 12.7 (0.98)*** | 2.1 (0.5)*** | |||||
| Age | Young | 1.0 (1.0) | 1.2 (0.8) | 0.2 (0.4) | ||||
| Old | −1.0 (1.0) | −1.2 (0.8) | −0.2 (0.4) | |||||
| Education | Low | 0.5 (0.6) | 0.3 (0.5) | −0.3 (0.2) | ||||
| High | −0.5 (0.6) | −0.3 (0.5) | 0.3 (0.2) | |||||
| Health literacy | Low | 0.0 (0.8) | 2.6 (0.6)*** | 0.9 (0.3)*** | ||||
| High | −0.0 (0.8) | −2.6 (0.6)*** | −0.9 (0.3)** | |||||
| Health numeracy | Low | −4.0 (0.7)*** | −0.2 (0.5) | −0.2 (0.3) | ||||
| High | 4.0 (0.7)*** | 0.2 (0.5) | 0.2 (0.3) | |||||
| Family history of RA | Not definitely | −1.9 (0.9)* | −2.7 (0.7)*** | −1.1 (0.3)*** | ||||
| Definitely | 1.9 (0.9)* | 2.7 (0.7)*** | 1.1 (0.3)*** | |||||
| DCE estimates | ||||||||
| Health literacy | Low | -a | -a | 17.8 (8.7) | 0.8;34.9 | 1.5 (0.9) | −0.2;3.2 | |
| High | 41.4 (6.4) | 28.9;53.8 | 13.9 (1.5) | 10.9;16.9 | 1.1 (0.4) | 0.4;1.8 | ||
| Numeracy | Low | 47.7 (12.0) | 24.1;71.3 | 6.1 (1.5) | 3.2;9.1 | -a | -a | |
| High | 59.1 (14.4) | 30.9;87.2 | 15.8 (2.1) | 11.8;19.9 | 0.8 (0.2) | 0.5;1.1 | ||
| Family history | Definitely | 30.4 (6.2) | 18.3;42.5 | 14.6 (4.3) | 6.3;22.9 | 1.0 (0.6) | −0.2;2.2 | |
| Not definitely | 47.5 (11.7) | 34.5;80.5 | 14.1 (1.6) | 10.9;17.3 | 1.0 (0.3) | 0.5;1.6 | ||
CI confidence interval, DCE discrete choice experiment, MA maximum acceptable risk, PTT probabilistic threshold technique, RA rheumatoid arthritis, SE standard error, *p < 0.1; **p < 0.05; ***p < 0.001
aSample size too small for a subgroup analysis