Although they elicit preferences and risk tolerance differently, discrete choice experiments and the probabilistic threshold technique lead to similar conclusions with regard to the general magnitude of maximum acceptable risk for serious adverse events.

Discrete choice experiments seem better suited in studies that aim to estimate the maximum acceptable risk for multiple risk attributes of differing severity.

The probabilistic threshold technique is likely better suited to measuring heterogeneity in the maximum acceptable risk estimates across a relatively small population, particularly for serious adverse events.

More respondents perceived the choice tasks of a discrete choice experiment to be easy or very easy to understand compared with those who rated the choice tasks of a probabilistic threshold technique the same way.