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. 2023 Oct 12;14:6156. doi: 10.1038/s41467-023-41876-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Regional association plot for Raynaud’s phenomenon (top), gene expression of IRX1 in skeletal muscle (middle), and gene expression of IRX1 in tibial artery (bottom). Summary statistics from logistic regression models for RP are from the present study whereas summary statistics from linear regression models were obtained from GTEx v8²². Colouring of SNPs is based on linkage disequilibrium with the lead RP variant (rs12653958) at this locus. Numbers in brackets indicate posterior probabilities (PP) for a shared genetic signal with RP based on statistical colocalization.