TABLE 4.
Effects of various antimicrobial compounds on the bioluminescence of recombinant S. mutans sensor bacteriaa
| Test agent (concn [μg/ml]) | % of bioluminescence of nontreated bacteria at the following times (h)b:
|
||||
|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | |
| Chlorhexidine (10) | 91 | 39.0 | 15.6 | 5.6 | 3.3 |
| Tetracycline (0.8) | 86 | 55.4 | 31.0 | 17.9 | 13.4 |
| Penicillin (0.4) | 91 | 87.4 | 56.6 | 27.9 | 19.7 |
a
The bacteria were incubated with the antimicrobial compounds at 35°C in BHI broth, and the bioluminescence was measured at the indicated time intervals.
b
The results are the means of two independent measurements. Variation between the measurements was less than 10%.