Table 2. Baseline Characteristics of Patients Admitted to the Intensive Care Unit for 48 Hours or More.
| Small-volume tubes (n = 10 261) | Standard-volume tubes (n = 10 940) | |
|---|---|---|
| Age, mean (SD), y | 63.5 (15.9) | 63.0 (16.1) |
| Age >70 y, No./total (%) | 3832/10 261 (37.3) | 4083/10 940 (37.3) |
| Sex, No. (%) | n = 10 260 | n = 10 911 |
| Female | 4090 (39.9) | 4178 (38.3) |
| Male | 6170 (60.1) | 6733 (61.7) |
| Most responsible diagnosis, No. (%)a | n = 9078 | n = 8515 |
| Cardiovascular | 2245 (24.7) | 1762 (20.7) |
| Nervous system | 1156 (12.7) | 1155 (13.6) |
| Respiratory | 1047 (11.5) | 881 (10.3) |
| Injury | 965 (10.6)b | 1577 (18.5)b |
| Other | 912 (10.0) | 641 (7.5) |
| Infection | 807 (8.9) | 676 (7.9) |
| Cancer | 779 (8.6) | 801 (9.4) |
| Digestive | 787 (8.7) | 728 (8.5) |
| Genitourinary | 216 (2.4) | 191 (2.2) |
| Endocrine | 164 (1.8) | 103 (1.2) |
| Female patients | ||
| Initial hemoglobin, g/dLc | ||
| Mean (SD) | 10.47 (2.10) | 10.59 (2.04) |
| Median (IQR) | 10.40 (8.90-11.90) | 10.60 (9.10-12.00) |
| Initial hemoglobin by level, No. (%), g/dLc | n = 3853 | n = 3912 |
| <7.0 | 128 (3.3) | 114 (2.9) |
| 7.0-<9.0 | 853 (22.1) | 771 (19.7) |
| 9.0-<11.0 | 1329 (34.5) | 1337 (34.2) |
| 11.0-13.0 | 1114 (28.9) | 1241 (31.7) |
| >13.0 | 429 (11.1) | 449 (11.5) |
| Male patients | ||
| Initial hemoglobin, g/dLc | ||
| Mean (SD) | 11.12 (2.45) | 11.20 (2.32) |
| Median (IQR) | 11.10 (9.30-12.90) | 11.20 (9.50-12.90) |
| Initial hemoglobin by level, No. (%), g/dLc | n = 5852 | n = 6335 |
| <7.0 | 196 (3.3) | 160 (2.5) |
| 7.0-<9.0 | 1030 (17.6) | 1002 (15.8) |
| 9.0-<11.0 | 1575 (26.9) | 1745 (27.5) |
| 11.0-13.0 | 1723 (29.4) | 1998 (31.5) |
| >13.0 | 1328 (22.7) | 1430 (22.6) |
| Creatinine, mg/dLc | ||
| Mean (SD) | 1.52 (1.48) | 1.40 (1.37) |
| Median (IQR) | 1.00 (0.74-1.57) | 0.95 (0.72-1.43) |
| Creatinine, No. (%), mg/dLc | n = 9025 | n = 10 113 |
| <1.5 | 6570 (72.8) | 7775 (76.9) |
| 1.5-3.0 | 1541 (17.1) | 1470 (14.5) |
| >3.0 | 914 (10.1) | 868 (8.6) |
SI conversion factor: To convert creatinine to μmol/L, multiply values by 88.4.
a
International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes. Data were provided by 20 of 25 participating intensive care units.
b
Standardized difference was greater than 0.1.
c
Data were provided by 24 of 25 participating intensive care units.