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. 2023 Apr 18;213(3):371–383. doi: 10.1093/cei/uxad041

Table 1.

Study population characteristics.

Kidney transplant recipients No rejection (n = 51) Rejection (n = 49) P
Age recipient (yrs) 55 (19–79) 63 (28–77) <0.01
Age donor (yrs) 55 (26–77) 63 (35–76) <0.01
Male gender recipient, % (n) 60.8 (31) 59.2 (29) 0.89
Male gender donor, % (n) 49 (25) 44.9 (22) 0.67
CMV-seropositivity recipient, % (n) 51 (26) 59.2 (29) 0.32
CMV-seropositivity donor, % (n) 51 (26) 57.1 (28) 0.48
CMV-serostatus donor/recipient 0.22
 −/− 27.4 (14) 16.3 (8)
 +/− 21.6 (11) 20.5 (10)
 −/+ 21.6 (11) 26.5 (13)
 +/+ 29.4 (15) 36.7 (18)
Mismatch HLA class I 2 (1-4) 3 (0–4) 0.76
Mismatch HLA class II 1 (0–2) 1 (1–2) 0.51
Mismatch HLA class I and II 4 (2–6) 5 (1–6) 0.97
PRA current (%) 0 (0–79) 0 (0–97) 0.65
PRA historic (%) 4 (0–100) 4 (0–97) 0.79
ABO incompatible, % (n) 0 (0) 4.1 (2) 0.04
Re-transplantation, % (n) 5.9 (3) 8.2 (4) 0.58
Underlying kidney disease 0.50
 Nephrosclerosis/atherosclerosis/hypertension 21.6 (11) 24.5 (12)
 Primary glomerulopathies 23.5 (12) 30.6 (15)
 Diabetes 19.6 (8) 18.4 (9)
 Urinary tract infections/stones 0 (0) 2 (1)
 Reflux nephropathy 7.8 (4) 0 (0)
 Polycystic kidney disease 9.8 (5) 8.2 (4)
 Other 17.6 (9) 14.3 (7)
 Unknown 3.9 (2) 2 (1)
Pre-emptive kidney transplantation, % (n) 35.3 (18) 34.7 (17) 1.00
Type of transplantation <0.01
 Living-unrelated 37.3 (19) 46.9 (23)
 Living-related 41.1 (21) 14.3 (7)
 Deceased 21.6 (11) 38.8 (19)
Time to biopsy-proven rejection (days post-transplant) 8 (2–341)
 TCMR I 26 (5–341)
 TCMR II 8 (2–259)
Acute T-cell-mediated rejection type*, % (n)
 TCMR I 35 (17)
 TCMR II 65 (32)

*Biopsy-proven T-cell mediated rejection within first year after transplantation.

Values are median (min–max) or proportion and number, respectively.