Table 1.
Study population characteristics.
Kidney transplant recipients | No rejection (n = 51) | Rejection (n = 49) | P |
---|---|---|---|
Age recipient (yrs) | 55 (19–79) | 63 (28–77) | <0.01 |
Age donor (yrs) | 55 (26–77) | 63 (35–76) | <0.01 |
Male gender recipient, % (n) | 60.8 (31) | 59.2 (29) | 0.89 |
Male gender donor, % (n) | 49 (25) | 44.9 (22) | 0.67 |
CMV-seropositivity recipient, % (n) | 51 (26) | 59.2 (29) | 0.32 |
CMV-seropositivity donor, % (n) | 51 (26) | 57.1 (28) | 0.48 |
CMV-serostatus donor/recipient | 0.22 | ||
−/− | 27.4 (14) | 16.3 (8) | |
+/− | 21.6 (11) | 20.5 (10) | |
−/+ | 21.6 (11) | 26.5 (13) | |
+/+ | 29.4 (15) | 36.7 (18) | |
Mismatch HLA class I | 2 (1-4) | 3 (0–4) | 0.76 |
Mismatch HLA class II | 1 (0–2) | 1 (1–2) | 0.51 |
Mismatch HLA class I and II | 4 (2–6) | 5 (1–6) | 0.97 |
PRA current (%) | 0 (0–79) | 0 (0–97) | 0.65 |
PRA historic (%) | 4 (0–100) | 4 (0–97) | 0.79 |
ABO incompatible, % (n) | 0 (0) | 4.1 (2) | 0.04 |
Re-transplantation, % (n) | 5.9 (3) | 8.2 (4) | 0.58 |
Underlying kidney disease | 0.50 | ||
Nephrosclerosis/atherosclerosis/hypertension | 21.6 (11) | 24.5 (12) | |
Primary glomerulopathies | 23.5 (12) | 30.6 (15) | |
Diabetes | 19.6 (8) | 18.4 (9) | |
Urinary tract infections/stones | 0 (0) | 2 (1) | |
Reflux nephropathy | 7.8 (4) | 0 (0) | |
Polycystic kidney disease | 9.8 (5) | 8.2 (4) | |
Other | 17.6 (9) | 14.3 (7) | |
Unknown | 3.9 (2) | 2 (1) | |
Pre-emptive kidney transplantation, % (n) | 35.3 (18) | 34.7 (17) | 1.00 |
Type of transplantation | <0.01 | ||
Living-unrelated | 37.3 (19) | 46.9 (23) | |
Living-related | 41.1 (21) | 14.3 (7) | |
Deceased | 21.6 (11) | 38.8 (19) | |
Time to biopsy-proven rejection (days post-transplant) | 8 (2–341) | ||
TCMR I | 26 (5–341) | ||
TCMR II | 8 (2–259) | ||
Acute T-cell-mediated rejection type*, % (n) | |||
TCMR I | 35 (17) | ||
TCMR II | 65 (32) |
*Biopsy-proven T-cell mediated rejection within first year after transplantation.
Values are median (min–max) or proportion and number, respectively.