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. 2023 Apr 18;213(3):371–383. doi: 10.1093/cei/uxad041

Table 2.

Proportions of donor-reactive cytokine producing CD137++ CD4 and CD8+ T cells for recipients receiving living and deceased donor kidneys

Living donor Deceased donor
CD137++
population of cyt pc *
Rejector (N = 30) Non-rejector
(N = 40)
P value Rejector (N = 18) Non-rejector (N = 11) P value
CD4+ polyfunctional (%) 0.006 0.004 0.015 0.004 0.004 0.669
 CD4+ triple+ (%) 0.001 0.000 0.003 0.001 0.001 0.573
 CD4+ double+ (%) 0.005 0.003 0.028 0.004 0.003 0.544
CD4+ single+ (%) 0.008 0.004 0.001 0.010 0.005 0.719
CD8+ polyfunctional (%) 0.007 0.002 0.024 0.011 0.012 0.753
 CD8+ triple+ (%)**
 CD8+ double+ (%) 0.006 0.002 0.025 0.010 0.012 0.753
CD8+ single+ (%) 0.022 0.010 0.017 0.026 0.021 0.787

*cyt pc, cytokine producing cells; % are of CD4+ and CD8+ T cells, respectively.

**CD8+ triple cytokine-producing cells were hardly detected and not included in this table.

Median values are depicted and values for R and NR are compared using the Mann–Whitney U test, P < 0.05 is considered statistically significant.