Table 1.

Delivery of CRISPR-Cas9 plasmid by EVs

EV source	Target organ/cells	Target gene	Loading method	Reference
SKOV3/HEK293T	tumor generated by SKOV3 xenografts	PARP-1	electroporation	Kim et al.48
HEK293FT	MSCs	hCTNNB1	liposomes	Lin et al.50
HEK293T	tumor generated by Raji-bearing xenograft	MYC	electroporation	Xu et al.53
HEK293T	pancreatic cancer	KrasG12D	Exo-Fect	McAndrews et al.49
DCs	chondrocytes	MMP-13	Lipofectamine 2000	Liang et al.51
MSC	spinal cord	TNF-α	electroporation	Wang et al.52