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. 2023 Sep 26;34:102040. doi: 10.1016/j.omtn.2023.102040

Table 2.

Delivery of CRISPR-Cas9 mRNA by EVs

EV source Target organ/cells Target gene Loading method Reference
Red blood cells MOLM13 cells miR-125b electroporation Usman et al.63
MDA-MB-231 cells HEK293T Reporter cell (mCherry) transfection (Lipofectamine2000) de Jong et al.65
HEK293T cells Liver C/ebpα transfection (Lipofectamine2000) Li et al.64