Table 4.

Some examples of peptides that can be added on EV surface to target specific organs/cells

Targeted cells/organs	Peptide	Reference
Glioma	RGE	Jia et al.104
CNS	RVG	Alvarez-Erviti et al.106
Intracranial glioblastoma	T7	Kim et al.107
Brain	ApoB	Choi et al.108
Glioblastoma	ApoA-I mimetic peptide	Ye et al.109
Muscles	CP05	Gao et al.110
Muscles and heart	T9	Wiklander et al.46
Muscles and heart	M12	Nance et al., Gao et al.140,141
Cardiomyocytes	IL-3	Bellavia et al.115
Cardiomyocytes	cardiomyocyte-specific peptide	Mentkowski et al.114
Heart	CTP	Zahid et al.116
Heart	PCM	Nam et al.117
Heart	ischemic myocardium-targeting peptide	Zhu et al.112
Heart	cardiac homing peptide	Vandergriff et al.113
Cartilage	chondrocyte affinity peptide	Liang et al.51
Pancreas	tetraspanin-8	Nazarenko et al., Rana et al.118,119
Cancer cells	GE11	Ohno et al.120
Cancer cells	TfR	Song et al.103
Cancer cells	glycans	Berenguer et al.122
Monocyte-derived DCs	MUC1	Koning et al.123