Table 4.
Association between selenium intake levels and BMD by sex.
| Variable | Range of selenium intake (µg/day) |
Male | Female | ||
|---|---|---|---|---|---|
| Model1 a | Model 2 b | Model1 a | Model2 b | ||
| β (p) | β (p) | β (p) | β (p) | ||
| Total femur BMD( gm/cm2) | |||||
| Dietary selenium (µg/day) | |||||
| Continuous (Per 1-SD increase) |
0.036(0.132) | 0.039(0.101) | 0.089(0.001) | 0.081(0.001) | |
| Q1 | ≤73.15 | Reference | Reference | ||
| Q2 | 73.16-98.55 | 0.017(0.590) | 0.018(0.578) | 0.036(0.131) | 0.033(0.165) |
| Q3 | 98.56-130.05 | 0.018(0.600) | 0.019(0.571) | 0.074(0.001) | 0.066(0.004) |
| Q4 | ≥130.06 | 0.072(0.040) | 0.078(0.025) | 0.083(0.001) | 0.078(0.001) |
| P for trend | 0.021 | 0.011 | 0.001 | 0.001 | |
| Total selenium (µg/day) | |||||
| Continuous (Per 1-SD increase) |
0.037(0.117) | 0.039(0.104) | 0.074(0.001) | 0.063(0.003) | |
| Q1 | ≤79.35 | Reference | Reference | ||
| Q2 | 79.36-110.05 | 0.026(0.410) | 0.031(0.328) | 0.030(0.210) | 0.024(0.307) |
| Q3 | 110.06-147.75 | 0.048(0.143) | 0.051(0.116) | 0.057(0.016) | 0.048(0.045) |
| Q4 | ≥147.76 | 0.068(0.047) | 0.074(0.032) | 0.084(0.001) | 0.074(0.001) |
| P for trend | 0.044 | 0.034 | 0.001 | 0.001 | |
| Femoral neck BMD( gm/cm2) | |||||
| Dietary selenium (µg/day) | |||||
| Continuous (Per 1-SD increase) |
0.023(0.325) | 0.024(0.300) | 0.082(0.001) | 0.078(0.001) | |
| Q1 | ≤73.15 | Reference | Reference | ||
| Q2 | 73.16-98.55 | 0.015(0.647) | 0.016(0.610) | 0.035(0.142) | 0.035(0.140) |
| Q3 | 98.56-130.05 | 0.030(0.364) | 0.031(0.343) | 0.068(0.003) | 0.063(0.001) |
| Q4 | ≥130.06 | 0.056(0.103) | 0.061(0.081) | 0.082(0.001) | 0.080(0.007) |
| P for trend | 0.072 | 0.055 | 0.001 | 0.001 | |
| Total selenium (µg/day) | |||||
| Continuous (Per 1-SD increase) |
0.024(0.311) | 0.024(0.312) | 0.069(0.001) | 0.063(0.003) | |
| Q1 | ≤79.35 | Reference | Reference | ||
| Q2 | 79.36-110.05 | 0.018(0.557) | 0.021(0.503) | 0.037(0.127) | 0.035(0.143) |
| Q3 | 110.06-147.75 | 0.051(0.115) | 0.053(0.100) | 0.058(0.015) | 0.052(0.031) |
| Q4 | ≥147.76 | 0.045(0.184) | 0.047(0.165) | 0.084(0.001) | 0.079(0.001) |
| P for trend | 0.192 | 0.189 | 0.001 | 0.001 | |
| Total spine BMD( gm/cm2) | |||||
| Dietary selenium (µg/day) | |||||
| Continuous (Per 1-SD increase) |
0.021(0.398) | 0.020(0.423) | 0.055(0.013) | 0.046(0.035) | |
| Q1 | ≤73.15 | Reference | Reference | ||
| Q2 | 73.16-98.55 | -0.006(0.860) | -0.008(0.814) | 0.001(0.982) | -0.006(0.812) |
| Q3 | 98.56-130.05 | 0.002(0.026) | -0.002(0.964) | 0.042(0.081) | 0.034(0.160) |
| Q4 | ≥130.06 | 0.033(0.360) | 0.031(0.389) | 0.066(0.008) | 0.059(0.017) |
| P for trend | 0.203 | 0.215 | 0.014 | 0.034 | |
| Total selenium (µg/day) | |||||
| Continuous (Per 1-SD increase) |
0.030(0.217) | 0.028(0.260) | 0.041(0.066) | 0.030(0.169) | |
| Q1 | ≤79.35 | Reference | Reference | ||
| Q2 | 79.36-110.05 | -0.004(0.892) | -0.007(0.832) | -0.002(0.937) | -0.008(0.741) |
| Q3 | 110.06-147.75 | 0.015(0.665) | 0.011(0.745) | 0.030(0.229) | 0.022(0.391) |
| Q4 | ≥147.76 | 0.043(0.228) | 0.039(0.273) | 0.052(0.032) | 0.043(0.075) |
| P for trend | 0.108 | 0.130 | 0.018 | 0.051 | |
a
Model 1 is shown as the odds ratio (95% confidence interval); adjusted for sex, body mass index, marital status and race.
b
Model 2 is shown as an odds ratio (95% confidence interval); further adjusted for history of hypertension, history of diabetes, history of osteoporosis in parents and history of previous fractures.
c
Model 3 is shown as odds ratio (95% confidence interval); further adjusted for education ,age and history of smoking.