Table 5.
Association between selenium intake levels and osteoporosis by sex.
| Variable | Range of selenium intake (µg /day) |
Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Model 1 a | Model 2 b | Model 1 a | Model 2 b | ||||||
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | ||
| Dietary selenium (µg/day) | |||||||||
| Continuous (Per 1-SD increase) |
1.000(0.994,1.006) | 0.980 | 1.002(0.996,1.007) | 0.585 | 0.995(0.991,0.999) | 0.009 | 0.996(0.992,1.000) | 0.030 | |
| Q1 | ≤73.15 | Reference | Reference | Reference | Reference | ||||
| Q2 | 73.16-98.55 | 0.899(0.370,2.185) | 0.814 | 1.035(0.143,2.591) | 0.942 | 0.849(0.594,1.212) | 0.367 | 0.867(0.603,1.247) | 0.442 |
| Q3 | 98.56-130.05 | 1.033(0.448,2.381) | 0.939 | 1.185(0.497,2.827) | 0.702 | 0.708(0.474.1.058) | 0.092 | 0.729(0.485,1.097) | 0.129 |
| Q4 | ≥130.06 | 0.567(0.224,1.435) | 0.231 | 0.741(0.281,1.955) | 0.544 | 0.560(0.344,0.911) | 0.020 | 0.617(0.376,0.961) | 0.045 |
| P for trend | 0.229 | 0.534 | 0.002 | 0.031 | |||||
| Total selenium (µg/day) | |||||||||
| Continuous (Per 1-SD increase) |
0.997(0.992,1.003) | 0.330 | 0.999(0.994,1.004) | 0.697 | 0.997(0.994,1.000) | 0.036 | 0.997(0.994,1.001) | 0.110 | |
| Q1 | ≤79.35 | Reference | Reference | Reference | Reference | ||||
| Q2 | 79.36-110.05 | 1.238(0.491,3.122) | 0.651 | 1.435(0.546,3.771) | 0.463 | 0.971(0.692,1.362) | 0.865 | 0.962(0.666,1.390) | 0.838 |
| Q3 | 110.06-147.75 | 1.608(0.696,3.715) | 0.267 | 1.976(0.818,4.770) | 0.130 | 0.676(0.462,0.988) | 0.043 | 0.716(0.475,1.080) | 0.111 |
| Q4 | ≥147.76 | 0.541(0.203,1.439) | 0.218 | 0.720(0.256,2.023) | 0.533 | 0.803(0.521,1.236) | 0.318 | 0.709(0.442,1.139) | 0.155 |
| P for trend | 0.139 | 0.412 | 0.027 | 0.074 | |||||
a
Model 1 is shown as the odds ratio (95% confidence interval); adjusted for body mass index, age, race, marital status, history of osteoporosis in parents and history of previous fractures.
b
Model 2 is shown as an odds ratio (95% confidence interval); further adjusted for history of hypertension, history of diabetes, education and history of smoking.